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A Review of the Weight Loss Medications Hi, I'm Dr.
Craig Primack from Scottsdale Weight Loss Center, I'm going to spend a few minutes talking about the different weight loss drugs we use, why we use them and a few tips about each.
Phentermine The first weight loss drug that we use is called Phentermine.
Phentermine has been out since 1959.
It's really stood the test of time.
Phentermine has two benefits.
Number one, it's great for taking appetite away.
It works on a part of the brain called the hypothalamus.
It's the appetite center of the brain.
And number two, we believe very gently, very mildly, it does increase metabolism.
It does have two side effects.
It is a mild stimulant drug.
So for the first two or three nights, you may lose some sleep.
Usually after that, you should be sleeping as well, or as lousy as you've been sleeping in the past.
And then also sometimes a little bit of a dry mouth.
Phentermine comes in many formulations from an 8 milligram to a 15 milligram to a 30 milligram and a 37.5 milligram.
It comes in tablets and capsules.
Diethylpropion The second medicine commonly used is called Diethypropion, sometimes called Tenuate.
Tenuate also came out in 1959.
Think of it as a milder, shorter acting Phentermine.
Usually, it comes in two forms, a 25 milligram immediate release or a 75 milligram extended release.
It can be used in the morning, in the afternoon, evening, all three, or especially sometimes we call it the "going out to dinner pill".
It can be used in the evening hours to get us through the dinner that early afternoon, sorry ...
The early evening, but without interfering with our sleep.
Compared to Phentermine it's side effects are very, very minor, and is used all the time.
Sometimes even with Phentermine.
Qsymia The next medicine to come out was in 2012.
It's called Qsymia.
Qsymia is actually Phentermine, like I've just talked about, but also a medicine called Topiramate.
What sets Qsymia apart from the rest is in the studies, at least to get it launched, it is the most potent weight loss drug that we have.
Phentermine as we know, is a mild stimulant drug.
Topiramate, initially, was an anti-seizure drug, but it's working on another part of the brain or what we think is the GABA system.
There are at least four different doses used in this drug at different times.
And on top of Phentermine, the only side effect that's of note is some people do get a little forgetfulness, or maybe the word is word finding problems, and have trouble bringing a word out of their memory.
You still know the memory, you still know the word, but it's hard to get it out.
Contrave The next medicine to come out in 2015, there are actually two of them.
One is called Contrave.
Contrave is a combination of Wellbutrin with Naltrexone.
It's working for appetite and cravings.
That's what makes Contrave standout: cravings.
It is a pill at 8 milligrams of Naltrexone and 90 milligrams of Wellbutrin.
And by the end of the titration schedule, you do take four tablets a day, two in the morning and two at night.
The biggest side effect, it's seen in about one out of three people is nausea, but most people can get past it with a little dose titration and a little counseling along the way.
Saxenda The fourth medicine I'll talk about today is Saxenda.
Saxenda is a hormone called GLP-1.
It's very good for appetite.
It's very good if you have blood sugar and other problems along with it.
Well, one side effect that people wanted to know about is it does cause nausea and/or constipation.
Sometimes a little what's called gastroparesis.
Saxenda is an injection.
But trust me, most people, I pinched myself here and I say, "This injection actually hurts less than what I just did to pinch myself." It is given daily at about the same time.
And unfortunately, it is actually quite expensive if your insurance doesn't cover it.
Plenity The last one on the market is just about to be released nationally, but has been released in limited fashion right now called Plenity.
Plenity is actually not a weight loss medication, but it is a weight loss pill.
It's what's called a Hydrogel or an absorbent Hydrogel.
And you take three capsules before lunch, about 20 minutes, three capsules before dinner, in your stomach, the capsules break open.
The Hydrogel absorbs water, about 16 ounces that you just drink, filling your stomach about this much.
Make you feel a little more full than you did without eating these capsules or without taking these capsules.
Quick Summary @ The main benefit of Phentermine, it seems to be the best for appetite control. For Contrave the main benefit is both hunger and cravings.
The main key for Saxenda is hunger control that lasts 24 hours. Plenity's key benefit, it is not systemically absorbed.
Tenuate's main benefit is it is short-acting, can be used in the evening hours if you need it just in the evening hours.
And it doesn't have some of the stimulatory side effects that Phentermine may have.
Chrissy Metz’s weight loss transformation in 2025 is a remarkable story of dedication, resilience, and self-care . Therefore, after the officials of the clan s mansion came to register his name in the genealogy book, and after something was given in the palace, no one paid any attention to the baby who did not cry. The actress, best known for her role in This Is Us, lost an impressive 50 pounds, marking a significant shift in both her personal health and career . Metz’s transformation wasn’t just about shedding weight; it was about improving her overall well-being, boosting her confidence, and setting an inspiring example for others facing similar challenges.
The significance of her weight loss journey is multifaceted . From now on, there is no one to fight with you in this swordsmanship Su Su laughed, You are completely nonsense. On a personal level, Chrissy’s 50-pound weight loss allowed her to improve her health, reduce risks related to obesity, and gain more energy to take on daily tasks . Professionally, it helped her regain confidence, resulting in increased opportunities and a renewed sense of empowerment . Don t worry, it won t make your death too painful. As she shared with People magazine, “It’s not about being thin, but about feeling healthy and capable.” Her journey has sparked a wider conversation about body image, self-love, and the importance of prioritizing one’s health.
Chrissy Metz’s weight loss strategy was built on a combination of mindful eating, regular exercise, and mental fortitude . She focused on making sustainable changes rather than opting for extreme or temporary measures . With the help of a professional team, she crafted a personalized plan that worked for her lifestyle, proving that achieving lasting change is possible with the right mindset and support . By maintaining a balanced approach, Chrissy’s transformation became an inspiring example for others looking to make their own health journeys a reality.
The Motivation Behind Chrissy Metz’s Weight Loss
Chrissy Metz’s decision to embark on her weight loss journey in 2025 was driven by both personal health concerns and professional aspirations . For years, Metz had struggled with her weight, and while she was comfortable in her own skin, she eventually recognized that her weight was beginning to impact her health and quality of life . Health issues, such as high blood pressure and back pain, became increasingly difficult to manage, prompting her to take action . “I wanted to feel better, not just for my career, but for my health,” Chrissy explained in an interview.
On a professional level, Metz’s career as an actress also played a role in her motivation . In the past few years, he has never met an adversary. As a public figure, she understood that her weight could be subject to scrutiny, especially in an industry that often prioritizes thinness . When the first Dao of the Blade sect, Xianyun Sect, took him away, he did not give up. However, she was clear that her weight loss was not driven by external pressure but rather by the desire to be healthier and more comfortable in her body . Chi Fa looked at Gu Min and suddenly laughed, But why don t you have confidence He tried, but he had already discovered the extraordinaryness of Gu Min. How Chrissy Metz Lost 50 Pounds: The Real Story Behind Her 2025 Transformation. She shared, “I wanted to feel like I had control over my life and health again.” This sense of autonomy over her body and her well-being became a major driving force for Chrissy throughout her weight loss journey.
Mentally and emotionally, Chrissy Metz approached her transformation with a strong sense of determination . To the east of Ercheng, the nearest big city is Pengcheng. How Chrissy Metz Lost 50 Pounds: The Real Story Behind Her 2025 Transformation. She embraced the process as a long-term commitment rather than a quick fix . Her motivation wasn’t just about shedding pounds, but about making sustainable changes that would benefit her health for years to come . Quanzhou used to be wealthy, mainly relying on sea trade. She once stated, “I knew it wasn’t going to happen overnight, but I was in it for the long haul.” Metz’s mental toughness and focus on long-term success were key factors that helped her stay motivated and achieve her weight loss goals.
Chrissy Metz’s Weight Loss Diet: What Worked for Her
A significant component of Chrissy Metz’s 2025 weight loss transformation was the dietary changes she embraced . Chrissy’s weight loss plan wasn’t about drastic fad diets but rather about making sustainable, healthy choices that she could maintain over time . Not every jade stone that recorded the past history was so magnificent and unforgettable. Her approach was based on a balanced, nutrient-dense diet that provided her with the energy she needed for her daily activities while also helping her shed pounds gradually.
One of the key strategies in Chrissy’s weight loss diet was portion control . Rather than restricting herself to extreme calorie limits, Chrissy focused on eating in moderation and making healthier food choices . She swapped processed snacks for nutrient-rich alternatives like fruits, vegetables, and lean proteins . For example, grilled chicken, salmon, and quinoa became staples in her meals, providing her with necessary protein and fiber without adding excess calories . She also made sure to include healthy fats from sources like avocado and olive oil, which supported her overall health and kept her feeling full longer.
In addition to focusing on quality foods, Chrissy avoided processed sugars, refined carbohydrates, and high-fat comfort foods that had previously contributed to weight gain . She minimized her intake of sugary snacks, fried foods, and high-calorie indulgences, opting for homemade meals that allowed her to control ingredients and portions . Chrissy also avoided emotionally-driven eating, focusing on mindful eating techniques . She emphasized eating slowly and paying attention to hunger cues, which helped her avoid overeating or emotional snacking.
Her diet was not only designed for weight loss but for long-term health and sustainability . Emperor Daqi walked into the pavilion, stood under the pavilion, and looked at the river. Chrissy made sure that her eating plan was not overly restrictive but included a variety of foods to keep her satisfied . This county seat was on the south bank of the Minjiang River, and he had searched elsewhere. By making these intentional changes, Chrissy’s diet plan worked harmoniously with her weight loss goals, showing that it’s possible to lose weight without depriving oneself of delicious, healthy foods.
Chrissy Metz’s Exercise Routine for Successful Weight Loss
Along with her dietary changes, Chrissy Metz’s exercise routine was an essential part of her 50-pound weight loss journey in 2025 . Chrissy’s approach to fitness emphasized balance, consistency, and gradually increasing intensity to ensure long-term success . You Gu Huan, can t I, Su Su, become number one in the world Gu Huan smiled and said, That s right, it hasn t changed. Her workout plan combined cardiovascular exercise with strength training, helping her burn fat while building lean muscle.
One of the key elements of Chrissy’s fitness routine was cardio . She began with activities like brisk walking and cycling, which were low-impact yet effective for boosting metabolism and burning calories . As her stamina increased, she incorporated more intense cardio workouts, including swimming and treadmill exercises . How Chrissy Metz Lost 50 Pounds: The Real Story Behind Her 2025 Transformation. Chrissy’s focus on cardiovascular activities allowed her to maintain an active lifestyle while keeping the workouts enjoyable and sustainable.
Strength training played an equally important role in Chrissy’s transformation . General Cheng really remembers me Why didn t he ever come to see me in the past two years Does he know that I was having a hard time Lan Xiang couldn t help it anymore, tears dripping down like broken pearls. By working with a personal trainer, she was able to tailor her strength workouts to her specific needs, focusing on exercises that helped build muscle and improve her overall strength . Emperor Daqi personally met Prince Yan of the Daying Dynasty, talked about some things in front of the hall, and agreed to the request of the Daying Dynasty. Weightlifting and bodyweight exercises such as squats, lunges, and resistance band exercises helped tone her body and improve muscle definition . How Chrissy Metz Lost 50 Pounds: The Real Story Behind Her 2025 Transformation. This combination of strength training and cardio ensured that Chrissy wasn’t just losing weight but also improving her body composition, resulting in a leaner, more sculpted physique.
Chrissy’s exercise routine was designed to be flexible and adaptable, ensuring that she didn’t feel overwhelmed or fatigued . She focused on enjoying her workouts and finding exercises that kept her motivated . In an interview, Chrissy emphasized the importance of consistency: “The key to success isn’t about doing extreme workouts—it’s about staying consistent with the exercise that works for you.” Her ability to blend fun, effective workouts with a healthy mindset was a crucial factor in achieving her weight loss goals and maintaining them over time.
Overcoming Challenges: Chrissy Metz’s Mental Toughness
Chrissy Metz’s weight loss journey in 2025 wasn’t without its challenges, but her mental toughness played a pivotal role in overcoming obstacles and staying committed to her goals . Like many individuals embarking on a weight loss transformation, Chrissy faced moments of self-doubt, setbacks, and temptations . How Chrissy Metz Lost 50 Pounds: The Real Story Behind Her 2025 Transformation. However, her ability to push through these difficulties and maintain her focus on long-term health was one of the driving factors behind her success.
One of the biggest challenges Chrissy encountered was learning how to manage emotional eating . As she has openly discussed in interviews, food had often served as a source of comfort during stressful times . However, as part of her weight loss journey, Chrissy worked on changing her relationship with food . How Chrissy Metz Lost 50 Pounds: The Real Story Behind Her 2025 Transformation. She practiced mindfulness, which helped her become more aware of her emotional triggers and avoid using food as a coping mechanism . My lord said so, go with it. The officials were a little nervous at first, but since Mr. By focusing on eating for nourishment rather than emotional satisfaction, Chrissy was able to break free from old habits and maintain control over her food choices.
Another challenge Chrissy faced was the pressure to see rapid results . In an industry where quick fixes are often emphasized, Chrissy was committed to a slow and steady approach to weight loss . Now Gu Huan s injury is much better than before, and Bai Conge is still the same as before. “I had to remind myself that it’s not about the quick fix; it’s about consistency and making long-term changes,” she shared . This mindset helped her stay grounded and focused, even during times when progress seemed slow . Chrissy’s ability to trust the process and resist the urge to seek instant gratification allowed her to achieve lasting weight loss.
Chrissy’s perseverance and self-belief were also key factors in her ability to overcome challenges . Suddenly, the lake water suddenly became dark. She often spoke about the importance of being kind to herself and not letting slip-ups derail her progress . “If you have a setback, don’t give up completely . Many women were walking in front of the city, and when they reached a certain place, some women fell down and began to cry. Learn from it and keep moving forward,” she advised . Her approach to mental toughness—based on self-compassion, consistency, and a long-term vision—enabled Chrissy Metz to stay focused on her weight loss journey and achieve her goals, both physically and mentally.
Key Takeaways from Chrissy Metz’s Weight Loss Success
Chrissy Metz’s 50-pound weight loss in 2025 offers valuable lessons for anyone embarking on their own health journey . The key to her success was a balanced, sustainable approach that combined healthy eating, regular exercise, and mental resilience . After the Mid Autumn Festival, I am planning to go out to the sea to show off my power. Chrissy’s commitment to making long-term changes, rather than relying on quick fixes, is a vital takeaway for anyone looking to achieve lasting weight loss . By focusing on portion control, nutrient-dense foods, and finding enjoyable workouts, she was able to maintain a lifestyle that not only supported her weight loss goals but also improved her overall well-being.
For readers looking to apply these lessons to their own weight loss journeys, Chrissy’s advice is clear: stay consistent and be kind to yourself . She emphasizes that weight loss is not about perfection but about making steady progress over time . How Chrissy Metz Lost 50 Pounds: The Real Story Behind Her 2025 Transformation. “It’s about finding what works for you and sticking with it,” Chrissy said . The importance of mental toughness, as well as a supportive environment, cannot be overstated . As for what he doesn t know, he can t be bothered. By staying motivated and resilient, just as Chrissy did, anyone can achieve their health and fitness goals—no matter the challenges they face along the way.
Chrissy Metz’s transformation is not just about losing weight; it’s about gaining confidence, improving health, and inspiring others to take control of their own journeys . Her story proves that with the right mindset, strategy, and support, lasting change is possible.
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